News list last updated on 20/01/2026
44 news
Fundamental research
Published on 20/12/2024
A grant of €640,500 from the Ligue Contre le Cancer for Prof. BACHY’s Team: Towards a New Approach to CAR T Cells
In response to the 2024 call for proposals of the Ligue Contre le Cancer "Innovative cell therapies in oncology: new vectors, new targets", Prof. Emmanuel BACHY's team has obtained a grant of € 640,500 for the project "Functional improvement of CAR-T cells by Boolean and epigenetic approaches".
This 3-year project is being carried out in collaboration with Prof. Olivier Hermine, Head of the Hematology Department at Necker Hospital and Director of Inserm Unit U1163 at the Imagine Institute in Paris, Prof. Michel Sadelain, Head of the Center for Cell Engineering at Memorial Sloan Kettering Cancer (MSKCC) in New York and Dr. Laurent Genestier, co-director of the Lymphoma Immunobiology team in Lyon (LIB) Inserm U1111-CNRS UMR 5308.
Clinical trials
Published on 17/12/2024
Valemetostat for patients with relapsed or refractory peripheral T-cell lymphoma (VALENTINE-PTCL01): a multicentre, open-label, single-arm, phase 2 study
Prof Pier Luigi Zinzani MD, Koji Izutsu MD, Neha Mehta-Shah MD, Stefan K Barta MD, Prof Kenji Ishitsuka MD, Raul Córdoba MD, Shigeru Kusumoto MD, Emmanuel Bachy MD, Kate Cwynarski PhD, Giuseppe Gritti MD, Anca Prica MD, Eric Jacobsen MD, Tatyana Feldman MD, Yann Guillermin MD, Daisuke Ennishi MD, Dok Hyun Yoon MD, Eva Domingo Domenech MD, Prof Jasmine Zain MD, Jie Wang MD, Prof Jin Seok Kim MD, ..., Steven M Horwitz MD
Read more
Events
Published on 07/12/2024
Dr Maël Heiblig in the spotlight: oral participation at ASH 2024
Session: 615. Acute Myeloid Leukemias: Clinical and Epidemiology: Genetic Markers and Outcomes in AML
Read more
Clinical trials
Published on 05/12/2024
Efficacy and safety of teclistamab in patients with relapsed/refractory multiple myeloma after BCMA-targeting therapies.
Touzeau C, Krishnan AY, Moreau P, Perrot A, Usmani SZ, Manier S, Cavo M, Martinez Chamorro C, Nooka AK, Martin TG, Karlin L, Leleu X, Bahlis NJ, Besemer B, Pei L, Stein S, Wang Lin SX, Trancucci D, Verona RI, Girgis S, Miao X, Uhlar CM, Chastain K, Garfall AL
Read more
Clinical trials
Published on 16/11/2024
Glofitamab plus gemcitabine and oxaliplatin (GemOx) versus rituximab-GemOx for relapsed or refractory diffuse large B-cell lymphoma (STARGLO): a global phase 3, randomised, open-label trial
Abramson JS, Ku M, Hertzberg M, Huang HQ, Fox CP, Zhang H, Yoon DH, Kim WS, Abdulhaq H, Townsend W, Herbaux C, Zaucha JM, Zhang QY, Chang H, Liu Y, Cheah CY, Ghesquieres H, Simko S, Orellana-Noia V, Ta R, Relf J, Dixon M, Kallemeijn M, Mulvihill E, Huang H, Lundberg L, Gregory GP
Read more
Clinical trials
Published on 16/11/2024
Ziftomenib in relapsed or refractory acute myeloid leukaemia (KOMET-001): a multicentre, open-label, multi-cohort, phase 1 trial
Eunice S Wang, Ghayas C Issa, Harry P Erba, Jessica K Altman, Pau Montesinos, Stephane DeBotton, Roland B Walter, Kristen Pettit, Michael R Savona, Mithun Vinod Shah, Marina Kremyanskaya, Maria R Baer, James M Foran, Gary Schiller, Lionel Adès, Mael Heiblig, Celine Berthon, Pierre Peterlin, Eduardo Rodríguez-Arbolí, Olga Salamero, Mrinal M Patnaik, Cristina Papayannidis, Jolanta Grembecka, Tomasz Cierpicki, Bradley Clegg, Joshua Ray, Brian M Linhares, Kun Nie, Amitava Mitra, Julie Mackey Ahsan, Marilyn Tabachri, Harris S Soifer, Daniel Corum, Mollie Leoni, Stephen Dale, Amir T Fathi
Read more
Published on 15/11/2024
Safety and efficacy of odronextamab in patients with relapsed or refractory follicular lymphoma
T M Kim, M Taszner, S Novelli, S-G Cho, J C Villasboas, M Merli, A Jiménez-Ubieto, B Tessoulin, L M Poon, D Tucker, J Walewski, S Yi, Y Song, G Chong, E Bachy, S Guidez, A Alonso, D Jagadeesh, W Zhang, L Magnano, E Iskierka-Jażdżewska, M Tani, B Shen, A Uppala, M Zhu, S Shariff, J Brouwer-Visser, A Chaudhry, H Mohamed, S Ambati, S Luminari; ELM-2 Investigators
Read more
Clinical trials
Published on 21/10/2024
Efficacy and Tolerance of Brexucabtagene Autoleucel in Adults with R/R B-ALL : A GRAALL study from the DESCAR-T registry.
Florence Rabian, David Beauvais, Tony Marchand, Sabine Furst, Anne Huynh, Eolia Brissot, Sebastien Maury, Ludovic Gabellier, Patrice Chevallier, Michael Loschi, Stéphanie Nguyen Quoc, Marie Balsat, Ingrid Lafon, Amandine Fayard, Vincent Camus, Célestine Simand, Niels Moya, Cristina Castilla-Llorente, Magalie Joris, Ana Berceanu…
Nicolas Boissel
Read more