IRCCS
Institut de
Recherche Clinique
sur les cancers et le sang

The IRCCS association acts as a driving force of progress in health, by providing the hematology department of Lyon Sud Hospital with a clinical research support structure encompassing all the necessary players.

393

Participating patients in 2024

25

People dedicated to hematology research

91.4%

satisfaction of our partners

Photo credits: Olivier Ramonteu

EXPERTISE

A European reference center in clinical research

A large network of patients

In 2024, 393 patients participated in a hematology clinical trial thanks to our structure, including 87 in early phase trials. Clinical studies are carried out in both myeloid and lymphoid hematology fields.

A center at the forefront of innovation

The treatments or treatment regimens evaluated today in clinical trials are the therapeutic strategies of tomorrow. Our center is at the forefront of medical innovation by offering our patients trials of new therapies, such as CAR-T cells or combined approaches limiting conventional chemotherapy.

More than 20 years of experience

Founded in 2000, IRCCS operational structure has become a major partner in clinical research in hematology, recognized as a third-party structure by the Hospices Civils de Lyon (HCL).

Browse the list of our trials

IRCCS stands out for its role as an intermediary between the different stakeholders (researchers, clinicians, patients, funders) and for its ethical and innovative commitment.

Latest publications

Find the latest news from IRCCS

Events Studies on data Published on 17/11/2025

Dr. Vincent Alcazer will present an oral communication at ASH 2025

Presentation ID 76 : A machine learning approach identifies a transcriptomic signature predicting treatment-free remission in chronic myeloid leukemia.

Events Published on 04/11/2025

SAVE THE DATE Post-regional ASH: March 6, 2026

Provisional program, subject to change: 9:00 AM: Welcome of participants: Prof. Bachy, Dr. Golfier 9:15 AM: Updates in allogeneic transplantation: Dr. Labussière, Prof. Bay, Dr. Cornillon 9:45 AM: Updates in AML and ALL: Dr. Heiblig, Dr. Carre, Dr. Balsat Coffee break 11:15 AM: Updates in myelodysplastic syndromes: Dr. Fossard, Prof. Park 11:45 AM: Updates in lymphomas: Prof. Ghesquieres, Dr. Carras, Dr. Sesques, Dr. Fouillet Lunch break 2:00 PM: Updates in benign hematology: Prof. Garban 2:15 PM: Updates in PNH, aplasias, and myeloproliferative syndromes: Dr. Alcazer, Dr. Barraco 3:15 PM: Updates in multiple myeloma: Dr. Karlin, DR. Lazareth, DR. Chalayer Coffee Break 3:45 PM: News in the LLC: Prof. Guiez, Dr. Ferrant 4:15 PM: Conclusions and Acknowledgments: Prof. Bachy

Clinical trials Published on 01/05/2025

TRANSCAR: Real-World outcomes of CD19CAR T Cell Therapy in relapsed/refractory transformed indolent lymphomas

Pierre Stephan, Roberta Di Blasi, Louise Roulin, Jean Galtier, Julien Calvani, Veronique Meignin, Marie Donzel, Alexandra Traverse-Glehen, Elsa Poullot, Marie-Cécile Parrens, Vivien Dupont, Alexandra Marquet, Steven Le Gouill , Roch Houot, Francois-Xavier Gros, François Lemonnier, Emmanuel Bachy, Catherine Thieblemont, Pierre Sesques

Join clinical research

Clinical research is one of the missions of the hematology department of Lyon Sud Hospital. It is ensured at the operational level by the IRCCS structure marked by:

Innovation

Our partners (academic or industrial societies) trust us to provide our patients with innovative therapies such as CAR-T cells or “first in Human” trials.

Multidisciplinary teamwork

The structure is entirely dedicated to clinical research. It manages all aspects of studies, namely all administrative procedures from the opening to the closing of the trials, but also treatment and monitoring of patients. All stakeholders share the desire to further research together with medical teams.

Professional development and expertise

- Work in a constantly evolving field, allowing you to broaden your technical and scientific skills - Benefit from continuing training through collaboration with multidisciplinary experts and participation in scientific conferences or congresses

Check out our job offers

The main mission of IRCCS is the organization and management of therapeutic or non-interventional studies of hematological cancers and blood diseases, including participation in national and international multicenter studies. A dedicated team of 25 clinical research professionals works within this structure integrated into the clinical hematology department of the Hospices Civils de Lyon at Lyon Sud Hospital.

Pr Hervé Ghesquières

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IRCCS Institut de Recherche Clinique sur les cancers et le sang