Clinical research at the IRCCS

IRCCS participates in health innovation. Thanks to the clinical trials carried out in the department, our structure helps pave the way for innovative treatments to improve the lives of patients and advance medicine.

Our flagship trials

Discover the major clinical trials carried out this year, at the heart of medical innovation
LAM (leucémie aigüe myéloblastique)

75276617ALE1001 (JANSSEN)

Étude de phase 1/2, première administration à l’homme de l’inhibiteur de Menin-KMT2A
(MLL1) Bleximenib chez des patients atteints de leucémie aiguë

Dr Mael HEIBLIG
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FL (Lymphome folliculaire)

CA073-1003_GOLSEEK-4 (BMS)

Étude de phase 3, multicentrique, randomisée, en ouvert, visant à comparer l’efficacité et la sécurité d’emploi du golcadomide en association avec le rituximab (Golca + R) versus le choix de l’investigateur chez des participants atteints de lymphome folliculaire en rechute/réfractaire (GOLSEEK-4)

Pr Emmanuel BACHY
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Myélome

KT-US-679-0788_iMMagine-3 (Kite-GILEAD)

Étude de phase 3, randomisée et en ouvert visant à comparer l’efficacité et l’innocuité du traitement par anitocabtagène autoleucel par rapport au traitement recommandé chez des participants atteints de myélome multiple en rechute/réfractaire

Dr Lionel KARLIN
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See all trials
Our added value

The advantages of our structure

The IRCCS association is committed to diversity, professional equality and the fight against harassment and discrimination.
At the forefront of innovation

– Asked about the latest international treatments (CAR T-cell)
– In charge of the first administrations to humans
– Integrated within a leading european hospital in hematology

Reactive

– Adjustable resources depending on the projects due to the flexibility of our small structure
– Versatile and expert staff who can adapt to new tests
– Reduced administrative times making it easier to start trials

Strong team involvement

– More than 20 years of know-how in the field
– Effective interdepartmental communication
– Competent staff dedicated to hematology
– Wide awareness allowing significant recruitment of patients

Become an IRCCS partner

If you wish to conduct a clinical trial in our hematology department and benefit from the operational structure of IRCCS, please use the contact link below:

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Our trials in figures

151
Number of trials in 2024
70
Number of phase I and II trials in 2024
+190%
of patients participating in trials in 10 years
+280%
trial in 10 years
Trials Categories

More than 150 clinical trials per year - Many pathologies concerned

In 2024, 151 clinical trials were carried out in the department thanks to our structure (80 trials in myeloid hematology and 71 in lymphoid hematology).

Pathologies lymphoïdes

Amylose
Autres lymphomes indolents
DLBCL (Lymphome diffus à grandes cellules B)
FL (Lymphome folliculaire)
HCL (Leucémie à tricholeucocytes)
LC (Lymphome cérébral)
LGL (Leucémie à grands lymphocytes granuleux T)
LH (Lymphome de Hodgkin)
LLC (leucémie lymphoïde chronique)
LT (Lymphomes et leucémies à cellules T)
MCL (Lymphome à cellules du manteau)
Myélome
Richter

Pathologies myéloïdes

aGVH (Réaction du greffon contre l'hôte aigüe)
Allogreffe
Aplasie médullaire
BPDCN (leucémies à cellules dendritiques plasmacytoïdes )
cGVH (Réaction du greffon contre l'hôte chronique)
Erythroblastopénie Immunologique
HPN (Hémoglobinurie paroxystique nocturne)
Infectieux
LAL (leucémie aigue lymphoblastique)
LAM (leucémie aigüe myéloblastique)
LMC (leucémie myéloïde chronique)
MF (Myélofibrose)
PV (Polyglobulie de Vaquez)
SMD (Syndrome myélodysplasique)
SMP (Syndrome myéloprolifératif)
TE (Thrombocytémie essentielle)
See all trials

Contact us

Do you want to conduct a clinical trial in our hematology department and benefit from the operational structure of the IRCCS? Contact us: