News list last updated on 07/05/2025
29 news

Clinical trials
Published on 01/01/2025
Patient-reported outcomes following ciltacabtagene autoleucel or standard of care in patients with lenalidomide-refractory multiple myeloma (CARTITUDE-4): results from a randomised, open-label, phase 3 trial.
Mina R, Mylin AK, Yokoyama H, Magen H, Alsdorf W, Minnema MC, Shune L, Isufi I, Harrison SJ, Shah UA, Schecter JM, Vogel M, Lendvai N, Gries KS, Katz EG, Slaughter A, Lonardi C, Gilbert J, Li Q, Deraedt W, Filho OC, Patel N, Florendo E, Karlin L, Weisel K
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Fundamental research
Published on 20/12/2024
A grant of €640,500 from the Ligue Contre le Cancer for Prof. BACHY’s Team: Towards a New Approach to CAR T Cells
In response to the 2024 call for proposals of the Ligue Contre le Cancer "Innovative cell therapies in oncology: new vectors, new targets", Prof. Emmanuel BACHY's team has obtained a grant of € 640,500 for the project "Functional improvement of CAR-T cells by Boolean and epigenetic approaches".
This 3-year project is being carried out in collaboration with Prof. Olivier Hermine, Head of the Hematology Department at Necker Hospital and Director of Inserm Unit U1163 at the Imagine Institute in Paris, Prof. Michel Sadelain, Head of the Center for Cell Engineering at Memorial Sloan Kettering Cancer (MSKCC) in New York and Dr. Laurent Genestier, co-director of the Lymphoma Immunobiology team in Lyon (LIB) Inserm U1111-CNRS UMR 5308.

Clinical trials
Published on 17/12/2024
Valemetostat for patients with relapsed or refractory peripheral T-cell lymphoma (VALENTINE-PTCL01): a multicentre, open-label, single-arm, phase 2 study
Prof Pier Luigi Zinzani MD, Koji Izutsu MD, Neha Mehta-Shah MD, Stefan K Barta MD, Prof Kenji Ishitsuka MD, Raul Córdoba MD, Shigeru Kusumoto MD, Emmanuel Bachy MD, Kate Cwynarski PhD, Giuseppe Gritti MD, Anca Prica MD, Eric Jacobsen MD, Tatyana Feldman MD, Yann Guillermin MD, Daisuke Ennishi MD, Dok Hyun Yoon MD, Eva Domingo Domenech MD, Prof Jasmine Zain MD, Jie Wang MD, Prof Jin Seok Kim MD, ..., Steven M Horwitz MD
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Events
Published on 07/12/2024
Dr Maël Heiblig in the spotlight: oral participation at ASH 2024
Session: 615. Acute Myeloid Leukemias: Clinical and Epidemiology: Genetic Markers and Outcomes in AML
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Clinical trials
Published on 05/12/2024
Efficacy and safety of teclistamab in patients with relapsed/refractory multiple myeloma after BCMA-targeting therapies.
Touzeau C, Krishnan AY, Moreau P, Perrot A, Usmani SZ, Manier S, Cavo M, Martinez Chamorro C, Nooka AK, Martin TG, Karlin L, Leleu X, Bahlis NJ, Besemer B, Pei L, Stein S, Wang Lin SX, Trancucci D, Verona RI, Girgis S, Miao X, Uhlar CM, Chastain K, Garfall AL
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Clinical trials
Published on 16/11/2024
Glofitamab plus gemcitabine and oxaliplatin (GemOx) versus rituximab-GemOx for relapsed or refractory diffuse large B-cell lymphoma (STARGLO): a global phase 3, randomised, open-label trial
Abramson JS, Ku M, Hertzberg M, Huang HQ, Fox CP, Zhang H, Yoon DH, Kim WS, Abdulhaq H, Townsend W, Herbaux C, Zaucha JM, Zhang QY, Chang H, Liu Y, Cheah CY, Ghesquieres H, Simko S, Orellana-Noia V, Ta R, Relf J, Dixon M, Kallemeijn M, Mulvihill E, Huang H, Lundberg L, Gregory GP
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Clinical trials
Published on 16/11/2024
Ziftomenib in relapsed or refractory acute myeloid leukaemia (KOMET-001): a multicentre, open-label, multi-cohort, phase 1 trial
Eunice S Wang, Ghayas C Issa, Harry P Erba, Jessica K Altman, Pau Montesinos, Stephane DeBotton, Roland B Walter, Kristen Pettit, Michael R Savona, Mithun Vinod Shah, Marina Kremyanskaya, Maria R Baer, James M Foran, Gary Schiller, Lionel Adès, Mael Heiblig, Celine Berthon, Pierre Peterlin, Eduardo Rodríguez-Arbolí, Olga Salamero, Mrinal M Patnaik, Cristina Papayannidis, Jolanta Grembecka, Tomasz Cierpicki, Bradley Clegg, Joshua Ray, Brian M Linhares, Kun Nie, Amitava Mitra, Julie Mackey Ahsan, Marilyn Tabachri, Harris S Soifer, Daniel Corum, Mollie Leoni, Stephen Dale, Amir T Fathi
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Published on 15/11/2024
Safety and efficacy of odronextamab in patients with relapsed or refractory follicular lymphoma
T M Kim, M Taszner, S Novelli, S-G Cho, J C Villasboas, M Merli, A Jiménez-Ubieto, B Tessoulin, L M Poon, D Tucker, J Walewski, S Yi, Y Song, G Chong, E Bachy, S Guidez, A Alonso, D Jagadeesh, W Zhang, L Magnano, E Iskierka-Jażdżewska, M Tani, B Shen, A Uppala, M Zhu, S Shariff, J Brouwer-Visser, A Chaudhry, H Mohamed, S Ambati, S Luminari; ELM-2 Investigators
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